The successful candidate will work closely with molecular biology laboratory staff and under the supervision of the Principal Investigator and a computational staff scientist.   Key responsibilities include executing and troubleshooting high-throughput (epi)genomic assays—such as Micro-C, CUT&RUN, RNA-seq, and ATAC-seq—across different species and cell types/tissues. The role will also involve analyzing next-generation sequencing data from these assays, using established pipelines and open-source bioinformatics tools, as well as integrating multi-omic data...

A Postdoctoral Scholar position with a bioinformatics/computational, experimental, or dual focus is available immediately in the laboratory of Dr. Brian J. O’Roak, Department of Molecular and Medical Genetics at Oregon Health & Science University (OHSU) for highly motivated individuals. Highlights of Dr. O’Roak’s past research successes include: pioneering trio-based exome sequencing in simplex autism and developing new technologies for rapid and economical targeted resequencing.   We are building on this experience by forming a strong and diverse research group focused on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular...

To perform, collect and analyze research procedures in all aspects of laboratory setting and ensure accuracy and progression of research projects, including but not limit to: - Collect and analyze research data - Keep accurate details of experimental procedures and original data - Prepare research summaries, abstracts, manuscripts - Develops and document standardized lab protocols, and assist with training of...

This position will assist in research that shows how temporal, spatial, and dose perturbation of oncogenes and tumor suppressor genes predispose to leukemia development and how we could use the leukemia-specific vulnerabilities, including the haploinsufficient phenotype observed in patients with chromosome and copy number deletions to develop synthesize lethal therapeutics.The selected candidate will participate in establishing project goals, defining short and long-term scientific strategies, and contributing to the generation of project-related documents and presentations.  -

This post-doctoral position is an exciting opportunity to develop a novel ex vivo organoid model system for multiple myeloma. You will be working with a group that has already created a similar model for acute myeloid leukemia and we have funding to look at creating a similar model for multiple myeloma. This project is both translational and basic science-focused, and the goal is to use this model to predict patient responses and study novel drug combinations. You will be working with a pharma team on the project, clinicians who take care of patients, and basic scientists in the lab—a great opportunity to make contacts in both academia and pharma. Ambitious post-doctoral fellows who want to...

The anxiety postdoctoral position emphasizes behavioral health and includes evaluation, treatment, and optional research activities within the Anxiety Treatment and Diagnostic Intake clinics. The post-doctoral fellow will provide diagnostic intake assessments, and outpatient intervention services to medically, developmentally, or psychologically complex or treatment refractory patients with anxiety and related disorders. Inpatient consultation service experiences are available and encouraged. Patients are primarily referred from OHSU subspecialty or general pediatric clinics and providers, or seen in response to inpatient consultation. Services will be provided primarily at Doernbecher...

- Clinical Research Coordination: screen, consent, collect data, and complete study visits as outlined in study protocols - Data analysis: be able to complete basic analysis of data; be able to convey statistical needs to team; work with department biostatistician on more complex analysis - Database Management:  build and maintain REDCap databases; abstract data from electronic medical record; upload data provided by system application analyst - Writing: write and submit abstracts to scientific...

- Clinical Research Coordination:  screen, consent, collect data, and complete study visits as outlined in study protocols  - Data analysis: be able to complete basic analysis of data; be able to convey statistical needs to team; work with department biostatistician on more complex analysis;  - Database Management:  build and maintain REDCap databases; abstract data from electronic medical record; upload data provided by system application analyst - Writing: write and submit abstracts to...

The Biomaterials and Biomechanics Department is seeking a Post-doctoral researcher/fellow to begin immediately. The successful candidate will be joining an enthusiastic and dynamic group. The lab is very active, with the opportunities to publish papers, submit grant proposals, present at technical meetings, and work with partners in industry and university / government.   There are currently several areas of work within my lab which span within the broad field of biomaterials and include the following specific topic areas: 1. Design and synthesis of novel polymeric materials for dental and biomedical applications: the major project funded in the lab aims at...

The successful candidate will work independently to investigate the molecular mechanisms that support health associated polymicrobial communities. He/she will be responsible for most of the planning, implementation, and data interpretation associated with his/her research. Thus, the candidate will be expected to work independently with attention to detail and strong record-keeping. The goal is to understand how the oral flora interacts and lead to early childhood caries disease development. This includes intra, inter microbial and potentially host interactions. Typical laboratory techniques often require expertise with gene expression analysis, targeted mutagenesis, microscopy, bacterial community analysis, and multiple `omics analysis.

The lab of Stephen Back, M.D., Ph.D. at Oregon Health & Science University (OHSU) in Portland, Oregon, in close collaboration with the laboratories of Jacob Raber, Ph.D.at OHSU and of Cecily Bishop, Ph.D.  at Oregon State University (OSU) in Corvallis, Oregon, is seeking a candidate for a Postdoctoral Research Associate position to study the effects of fetal and neonatal intermittent cerebral hypoxemia on brain development.  The lab currently has NIH funding for studies to explore the sequelae of maternal sleep apnea on fetal and postnatal brain development.  Despite the fact that maternal sleep apnea commonly occurs in roughly 20-40% of human pregnancies, the long-term impact on brain...

- Designing and conducting both wet and dry laboratory experiments. - Dry lab experience: Includes programming, utilizing machine learning libraries, and developing predictive models.  - Wet lab experience: Encompasses protein purification, biochemistry, microbiology, and cell biology techniques - Generally maintaining laboratory and research space, laboratory notebooks and logs, etc. - Participating in lab meetings, making contributions and submitting research for publication, submitting applications for research funding, presenting research at seminars, poster sessions and conferences.

Technical Research: Independently conduct cutting-edge research on the development and delivery of various gene correction constructs using both in vitro and in vivo models. These responsibilities include: - design and optimize gene editing constructs for targeted genome modifications, - employ iPSC derivation techniques and perform thorough characterization to ensure the quality and integrity of cell lines used in the research, - day to day maintenance of cell cultures, - perform molecular, histological, and immunocytochemical analyses to evaluate the effects of genome editing on targeted cells and tissues, - implement effective methodologies to deliver gene editing constructs into fibroblasts and iPSCs,...

Key Responsibilities & Performance Standards Technical Researh:

We are looking for a post-doctoral researcher with a background in computer, information, or data science, with an interest in stream processing. This will focus on development of algorithms to process data in near-real time as it streams to servers from research participants. This position is anticipated to last 1.5-3 years to allow adequate time for the researcher to integrate with the team, understand the current platform infrastructure and data streams, and contribute to the research.  Position may be hybrid with possibility of becoming remote, with workspace available at OHSU’s main campus in Portland, OR.  Some...

We are looking for a post-doctoral researcher with an interest in algorithm development of analytics for the large, diverse data sets generated by ORCATECH research projects.  This position is anticipated to last 1.5-3 years to allow adequate time for the researcher to integrate with the team and understand the available data.  Position may be hybrid or remote, with workspace available at OHSU’s main campus. Some travel may be required for conference presentations.  

The anxiety postdoctoral position emphasizes behavioral health and includes evaluation, treatment, and optional research activities within the Anxiety Treatment and Diagnostic Intake clinics. The post-doctoral fellow will provide diagnostic intake assessments, and outpatient intervention services to medically, developmentally, or psychologically complex or treatment refractory patients with anxiety and related disorders. Inpatient consultation service experiences are available and encouraged. Patients are primarily referred from OHSU subspecialty or general pediatric clinics and providers, or seen in response to inpatient consultation. Services will be provided primarily at Doernbecher...

- Synthetic design and development of novel fluorophores to specifically highlight tissues in the body for fluorescence guided surgery. - Attendance and presentation at lab meetings, contributions to publications as requested (writing, figures, data), contributions to applications for funding as requested (writing, figures, data). - Presentations of successful research at one or more national or international meetings per year, as requested. - Supervision of graduate or other students as requested.

- Work on research experiments relating to the Cell Fusion/cyclic immunostaining project as assigned by Drs. Melissa Wong and Summer Gibbs. These studies will include a variety of technical approaches including: cell culture, cell imaging, immunohistochemical, tissue scanning and evaluation, antibody validation, computational analyses. - Sample collection and processing. Interaction with clinical staff to facilitate identification and collection of samples. Possible consenting of patients onto IRB approved protocol.  - Perform data analyses and entry and maintain data files on research projects utilizing various platforms (Microsoft Excel, Microsoft Access, RedCap, caTissue, ClinPortal,...

- Designing and performing laboratory experiments. - Generally maintaining laboratory and research space, laboratory notebooks and logs, etc. - Participating in lab meetings, making contributions and submitting research for publication, - Submitting applications for research funding, presenting research...