Oregon Health & Science University

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Job Locations US-OR-Beaverton
The laboratory of Dr. Paul Kievit has a postdoctoral position available in the Division of Cardiometabolic Health at the Oregon National Primate Research Center at Oregon Health & Sciences University. A major focus in our group is examining the reciprocal relationship between obesity-associated changes in metabolism & systemic inflammation and infectious diseases. Current projects study the impact of obesity in nonhuman primate models of HIV and SARS-CoV-2. All studies depend on a highly collaborative work environment within the lab, ONPRC, and external collaborators. The experiments proposed include physiological measurements of metabolism to examine glucose and insulin homeostasis, measurements of body composition, serum profiles, and microbiome analysis. In addition, there will be extensive ex-vivo analysis of organ specific metabolism (ie pancreas, brain, fat, liver) to generate molecular mechanistic data as well as transcriptomic data analysis from single cell and single nuclei RNAseq data sets.  Responsibilities will include: - Assisting at multiple phases of the study, including data collection, data analysis, and results dissemination by publications and presentations at national meetings. - Plans, conducts and completes laboratory experiments. Performs primary molecular techniques which could include cell culture (including primary cell isolation and culture), flow cytometry, PCR, DNA/RNA assays, enzymatic assays, microscopy, tissue collection and analysis including IHC staining.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Oregon National Primate Research Center (ONPRC)
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2022-19226
Job Locations US-OR-Beaverton
The laboratory of Dr. Paul Kievit has a postdoctoral position available in the Division of Cardiometabolic Health at the Oregon National Primate Research Center at Oregon Health & Science University. A major focus in our group is studying the impact of environmental conditions on early life and the link to health/disease in childhood and adult life, often referred to as the Developmental Origin of Health and Disease (DOHaD) hypothesis. We have funding to study the impact of obesity, gastric bypass surgery and/or exposure to diabetic treatment drugs in a nonhuman primate model on maternal health, pregnancy, fetal development, and early childhood development. All studies depend on a highly collaborative work environment within the lab, ONPRC, and external collaborators. The experiments proposed include physiological measurements of metabolism to examine glucose and insulin homeostasis, measurements of body composition, serum profiles, monitoring of pregnancy and fetal growth via ultrasound, and microbiome analysis. In addition, there will be extensive ex-vivo analysis of organ specific metabolism (i.e. pancreas, brain, fat, liver) to generate molecular mechanistic data.  Responsibilities will include: - Assisting at multiple phases of the study, including data collection, data analysis, and results dissemination by publications and presentations at national meetings.  - Plans, conducts and completes laboratory experiments. Performs primary molecular techniques which could include cell culture (including primary cell isolation and culture), flow cytometry, PCR, DNA/RNA assays, enzymatic assays, microscopy, tissue collection and analysis including IHC staining.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Oregon National Primate Research Center (ONPRC)
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2022-19190
Job Locations US-OR-Beaverton
Dr. Burwitz’s lab focuses on Hepatitis B virus (HBV) infection of non-human primates. This novel model is currently being refined for the testing of therapeutic and curative approaches towards HBV. This post-doctoral scholar will assist Dr. Burwitz with project management, ranging from conception of appropriate experiments to management of large scale non-human primate studies. In addition, they will help Dr. Burwitz identify key advancements in the HBV field and will work independently to ensure additional funding to the group. They will also manage a small group of technicians and/or graduate students, which they will utilize to maximize scientific output from the group.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vaccine and Gene Therapy Institute
Postion Category
Research
HR Mission
Research
Requisition ID
2022-18141
Job Locations US-OR-Beaverton
Postdoctoral positions are available for a newly NIAAA-funded study in the Division of Neuroscience at the Oregon National Primate Research Center at the Oregon Health & Sciences University. This project is a collaboration between the laboratories of Drs. Chris Kroenke, Elinor Sullivan, and Verginia Cuzon Carlson. Together, our group is studying the effects of prenatal ethanol exposure in a non-human primate model of fetal alcohol spectrum disorder. The experiments proposed include magnetic resonance imaging, ex vivo slice electrophysiology, and primate behavior including the assessment of normative behavior, cognition and emotional regulation.  Responsibilities will include assisting at multiple phases of the study, including data collection, data analysis, and results dissemination by publications and presentations at national meetings.  Candidates with expertise or prior experience in one of the following areas (and a strong desire to develop additional skills in at least one additional area) are especially encouraged to apply: behavioral models of learning and motivation, models of alcohol use disorder, developmental neuroscience, ex vivo slice electrophysiology, neuroimaging data and/or computational neuroscience.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Oregon National Primate Research Center (ONPRC)
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2021-11192
Job Locations US-OR-Beaverton
Uncontrolled inflammation generates significant morbidity and mortality in many diseases of infectious (e.g. HIV, Mtb) and non-infectious (e.g. inflammatory bowel disease) origin. By utilizing a variety of non-human primate models of human diseases, the Estes Laboratory works to elucidate determinants of local and systemic inflammation leading to tissue pathology, disease progression, and pathogen persistence, as well as test therapeutics to modulate the immune landscape, restore immune homeostasis, and reduce pathogen tissue reservoirs.    The Estes Lab is currently recruiting a highly self-motivated and energetic postdoctoral researcher to lead a project within the new multi-center Cascade IMPAc-TB consortium, an ambitious NIH contract designed to accelerate progress in tuberculosis vaccine development. In collaboration with the Gerner Lab in Seattle, this project is designed to provide a spatial framework, via advanced in situ hybridization and immunofluorescent techniques, that will complement and synergize with other consortium projects. Additionally, this individual will also lead and collaborate on other projects within the lab, including projects to understand HIV/SIV reservoir dynamics. Background in a relevant immunology lab is required. Direct experience working on TB, HIV/SIV, non-human primate models, multiplexed in situ hybridization and protein immunofluorescence, and/or multispectral imaging is highly desirable.   Please note that this position is at OHSU's West Campus (Beaverton). Submit a resume, cover letter, and at least three references to be considered for this position.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vaccine & Gene Therapy Institute
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2020-6311
Job Locations US-OR-Beaverton
A postdoctoral fellowship position is available in the laboratory of Dr. Jonah Sacha within the Vaccine & Gene Therapy Institute and the Oregon National Primate Research Center at the Oregon Health & Science University in Portland, Oregon. This position will support a newly funded research project focusing on testing a new, clinically relevant approach to HIV cure and prevention. The successful candidate will join a highly productive and interactive research group exploring transplant immunology, Cytomegalovirus vaccine vector-induced immunity, and HIV virology using the macaque model of human disease.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vaccine and Gene Therapy Institute
Postion Category
Student
HR Mission
Research
Requisition ID
2020-5860

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