Generate and grow iPSCs and human retinal organoids, evaluate therapeutics in the generated iPSCs and retinal organoids, characterize retinal disease features and gain a mechanistic understanding for the development of BBS7-mediated retinal disease.   Develop a rhesus macaque retinal organoid model system as a precursor for testing therapies in nonhuman primate models, including newly developed therapeutics and/or cell transplantation.

Grant writing – Applicant will submit a grant that fits the scope of their research and the stage of their career.   Manuscript writing – Applicant will submit a publication summarizing their research.   Applicant will manage and execute all experiments associated with their research project. The research project available consists of evaluating gene editing approaches in human stem cells and human retinal organoids. Experience working with iPSCs is preferred.   Applicant will perform necessary administrative paperwork to facilitate their research. This may include ordering supplies, regulatory approvals, etc  

Animal handling of rodents.   Multi-electrode array recordings from the ex-vivo mammalian retina. Presentation of their research at multi-PI meetings and research conferences. Data analysis and manuscript preparation.