Oregon Health & Science University

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Job Locations US-OR-Beaverton
Postdoctoral positions are available for a newly NIAAA-funded study in the Division of Neuroscience at the Oregon National Primate Research Center at the Oregon Health & Sciences University. This project is a collaboration between the laboratories of Drs. Chris Kroenke, Elinor Sullivan, and Verginia Cuzon Carlson. Together, our group is studying the effects of prenatal ethanol exposure in a non-human primate model of fetal alcohol spectrum disorder. The experiments proposed include magnetic resonance imaging, ex vivo slice electrophysiology, and primate behavior including the assessment of normative behavior, cognition and emotional regulation.  Responsibilities will include assisting at multiple phases of the study, including data collection, data analysis, and results dissemination by publications and presentations at national meetings.  Candidates with expertise or prior experience in one of the following areas (and a strong desire to develop additional skills in at least one additional area) are especially encouraged to apply: behavioral models of learning and motivation, models of alcohol use disorder, developmental neuroscience, ex vivo slice electrophysiology, neuroimaging data and/or computational neuroscience.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Oregon National Primate Research Center (ONPRC)
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2021-11192
Job Locations US-OR-Portland
This position will work within teams to tackle challenges in understanding mTOR signaling pathway in advanced bladder cancer. The candidate is expected to maintain a high level of productivity in the laboratory setting and demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise. Duties include: - Work with current and emerging teams to tackle challenges in understanding mTOR signaling pathway in advanced bladder or renal cancer. Maintain a high level of productivity in the research. - Participate in weekly group meetings and individual (1:1) meetings with the PI. - Write and publish research results in peer-reviewed journals and present work at scientific conferences. - Actively seek research grant opportunities (such as postdoctoral individual National Research Service Award (NRSA)) to facilitate career goals. - Build good relationships with peers, mentoring the junior colleagues and cross functionally with partners outside of teams to seek a good inter-laboratory collaboration. - Help keep the laboratory organized and maintain GLP-like standard research records. Salary for this position aligns with the NIH Salary Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Pathology and Laboratory Medicine
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-11164
Job Locations US-OR-Portland
Key Responsibilities of this Position: - Designing and performing laboratory experiments. - Generally maintaining laboratory and research space, laboratory notebooks and logs, etc. - Participating in lab meetings, making contributions and submitting research for publication, submitting applications for research funding, presenting research at seminars, poster sessions and conferences.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Molecular Microbiology and Immunology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2019-1955
Job Locations US-OR-Portland
The successful candidate will work independently to molecular mechanisms used by different oral microbes to communicate with each other and to create robust biofilms within the oral cavity and other body sites. The study involves the understanding of how oral commensal bacteria can interact with potential pathogens to modulate their virulence properties.  He/she will be responsible for most of the planning, implementation, and data interpretation associated with his/her research. Thus, the candidate will be expected to work independently with attention to detail and strong record-keeping. The goal is to understand what signals the commensal sends to keep the pathogens in check and what factors may upset pathogens to enhance their virulence.  Typical techniques often involved include real-time PCR, western blot, protein expression/purification, coimmunoprecipitation, protein-protein/RNA-RNA interaction assays, gene expression analysis, targeted mutagenesis, and microscopy. Demonstrable experience with these techniques is preferred. As a postdoctoral scholar, the candidate may also be involved with the training and supervision of students and junior staff as well as play an integral role in the management and supply ordering for the laboratory. Assistance with the development and preparation of grants/manuscripts will also be expected.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
School of Dentistry, Research
Postion Category
Dental
HR Mission
Academics
Requisition ID
2021-10436
Job Locations US-OR-Portland
This is a junior level PhD post-doctoral researcher position and will provide a mechanism for the hired individual to develop into a successful independent researcher in the fields of cell and developmental biology.   The lab uses zebrafish as a model system to study mechanisms of the peripheral sensory system development and function. The Postdoc will use variety of modern approaches, including transgenesis, CRISPR-based genome editing, single-cell RNA sequencing (scRNA-seq), and live imaging, to dissect intracellular processes that drive axon growth, neurotrophin signaling, and collective cell migration during development and disease.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental & Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-9764
Job Locations US-OR-Portland
This is a junior level PhD postdoctoral researcher position. This position will provide a mechanism for the hired individual to develop into a successful independent researcher in the fields of cell and developmental biology. The lab uses zebrafish as a model system to study mechanisms of the peripheral sensory system development and function. The hired individual will use variety of modern approaches, including transgenesis, CRISPR-based genome editing, single-cell RNA sequencing (scRNA-seq), and live imaging, to dissect intracellular processes that drive axon growth, neurotrophin signaling, and collective cell migration during development and disease.   Salary for this position aligns with the NIH Scale.   Work is generally 40 hours per week during normal working hours, however, some evening and weekend work will be necessary on occasion. Additional safety training will be required to work with cell lines/ infectious bacteria or viruses/ working with in a BSL-2 environment. Use of dosimeter and adherence to radiological safety ordinances is required. Working with laboratory animals is required.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental and Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-9765
Job Locations US-OR-Portland
The postdoctoral researcher on this project would be expected to conduct statistical and computational analyses and to lead manuscript preparation. There is ample opportunity to be lead author on new papers with already-available data, or to carry out specialized analyses, or both depending on career goals.   The candidate will also have the opportunity for advanced training in developmental psychopathology, translational research conceptualization, genomics/epigenomics, statistics, bioinformatics, and machine learning. Training opportunities will be developed commensurate with the interests and skills of the candidate. The position will provide one year of guaranteed funding, with a second year contingent on performance and funding availability. The training faculty include but are not limited to Joel Nigg, Ph.D., Michael Mooney, Ph.D., Nathan Dieckmann, Ph.D., Xubo Song, Ph.D., and Bonnie Nagel, Ph.D. Duties include:   - Analysis and write up of data for publication and presentation of data at national and international meetings - Conceptualization of data and explanation to others, including data collection staff - Attend collaborator, staff, lab, and other necessary meetings
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Department of Psychiatry, Psychology Clinical Research
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-9619
Job Locations US-OR-Portland
A full time Postdoctoral Scholar position is available at OHSU at the Department of Anesthesiology and Perioperative Medicine focusing on the mechanisms of stroke in white matter (WM) as a function of age. Epigenetic regulation of post-injury recovery and preconditioning of brain against injury are the main areas of focus. The Postdoctoral Scholar will participate in high impact research at the intersection of experimental neuroscience, neuroimaging and clinical translation.   Responsibilities include performing in vitro and in vivo stroke models, electrophysiology experiments, and protein assays and biochemical experiments, and processing tissue samples for imaging, including live and fix specimens, generating data utilized for both grant and publication applications. The successful candidate will also participate in academic development, hypothesis generation, experimental planning, data interpretation; training and coaching students and junior staff; and grant and publication writing.   The fellow will have the opportunity to learn experimental approaches in our lab such as optic nerve and corpus callosum slice models, employing electrophysiological recordings, and advanced microscopy techniques such as confocal, two-photon microscopy and 3D electron microscopy. The fellow will work as part of a multidisciplinary research team including neuroscientists and imaging scientists. A high level of engagement in these projects, including the ability to provide pivotal conceptual and technical input, is essential.   Salary for this position will align with the NIH Scale.   The OHSU Fellowship for Diversity in Research seeks to address the need for increased representation of minoritized races/ethnicities in STEM at the postdoctoral level. Eligible candidates are encouraged to apply. Visit www.ohsu.edu/ofdir for more information.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Anesthesiology and Perioperative Medicine
Postion Category
Research
HR Mission
School of Medicine
Requisition ID
2021-9061
Job Locations US-OR-Portland
- Designing research project; performing laboratory research; collecting and analyzing data; organizing data for presentation; writing manuscript - Preparing grant applications and submitting postdoctoral fellowships - Contributing to other projects in the lab and training junior lab members Salary for this position will align with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental and Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-8597
Job Locations US-OR-Portland
Postdoctoral Fellow  position will perform research on delivery of gene therapies in Cystic Fibrosis.  The position will be expected to participate in journal clubs, attend seminars, departmental retreats, and generally take advantage of as many educational opportunities at the University as possible. - The position will also be expected to: - Assist in research design and execution - Supervise technical personnel, and students - Assist in the preparation of grant applications, presentations, and manuscripts - Other duties as assigned.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Pediatrics
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-8468
Job Locations US-OR-Portland
A Postdoctoral Scholar is being recruited to work on one or more projects. Potential projects include (1) developing new mathematical models to describe the glucoregulatory system of people with type 1 diabetes during exercise, (2) development of new prediction algorithms for predicting hypoglycemia and other glycemic excursions using big data analytics, (3) developing new control algorithms for automated delivery of insulin and glucagon within a smart-phone based system. The position will require skills for the development of models and machine learning algorithms that can be used both within an automated drug delivery system and within a decision support framework. The Postdoctoral Scholar will independently write and submit grants and technical research papers and to prepare and give oral / poster presentations at international conferences. The Postdoctoral Scholar will come up with original ideas and work towards proving them and ultimately getting them funded through the grant submission process. The candidate should expect to work hard to move forward on a pathway to becoming an independent faculty member.   Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Department of Biomedical Engineering
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-8104
Job Locations US-OR-Portland
The purpose of this position is to conduct research in the lab of Dr. Jacoby. The Postdoc will work on a project characterizing abnormalities in the nerves controlling the airways in asthma. This position will require knowledge of cell biology and animal models of disease. Responsibilities include:   - Participate in lab research - Design and perform experiments on intergenerational transmission of asthma - Expose lab animals to antigens, viruses, and other asthma relevant treatment - Measure airway physiology - Process lung tissues for histological analysis - Perform quantitative histology and analyze results - Perform and analyze relevant DNA methylation studies - Use quantitative RT-PCR to measure gene expression and validate the effects of DNA methylation. - Prepare results for publication and presentation - Attend and present technical status reports at meetings - Other duties as assigned
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Pulmonary & Critical Care Medicine
Postion Category
Research
HR Mission
School of Medicine
Requisition ID
2020-6552
Job Locations US-OR-Portland
- Planning, executing, and analyzing experiments for independent research project(s) using biochemical methods and single particle and tomographic cryo-EM methods to elucidate the structure of the MET complex. - Manuscript preparation for individual projects and assisting other lab members with manuscripts as needed. - Assisting the PI and other lab members with grant application (data acquisition, writing assistance, editing) as needed. - Traveling to national and international meetings to present on findings. - Helping to mentor and train junior members of the laboratory.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vollum Institute
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2020-7591
Job Locations US-OR-Portland
We are seeking a motivated Postdoctoral Fellow to conduct research in areas of tumor immunology and tumor microenvironment, identifying cells and their mediators, and epigenetic mediators of inflammation that critically regulate cancer development. Specific projects will be determined by the applicant’s skill set and articulated research interests. Experience in immunology, ex vivo tissue culture-based assays, and mouse models of cancer are a requisite.   The Postdoctoral Fellow will be the primary strategist in scientific aspects of the assigned project, and in that regard may participate in supervision of some activities of research assistants, frequently taking responsibility for expensive equipment and experiment design. It is expected that the Postdoctoral Fellow will write scientific papers, abstracts, and submit manuscripts for publication and seek out and apply for grants and additional funding to support this research.   Curriculum vitae (CV), one-page research description with relevant publications, and names/contact information for at least three professional references, should be uploaded with the application   Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental and Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-5585
Job Locations US-OR-Portland
Postdoctoral position will focus on the discovery and validation of new therapeutic targets in hematologic malignancies and the molecular characterization of somatic changes and aberrant signaling pathways underlying disease pathogenesis.  Candidates are expected to have substantial experience in molecular biology, biochemical techniques, and in vivo studies.  In addition to wet lab capabilities the optimal candidate will also have experience in working with large annotated datasets. A basic understanding of genomic analyses methods and/or use of computational methods for identifying common mutations and activated pathways would be highly valuable.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Pediatrics
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-3690
Job Locations US-OR-Portland
- Planning, executing, and analyzing experiments for independent research project(s) using electrophysiology, molecular, cellular, and live imaging approaches in the rodent brain. - Manuscript preparation for individual projects and assisting other lab members with manuscripts as needed. - Assisting the PI and other lab members with grant application (data acquisition, writing assistance, editing) as needed. - Traveling to national and international meetings to present on findings. - Helping to mentor and train junior members of the laboratory.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vollum Institute
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2020-6983
Job Locations US-OR-Beaverton
A full-time Postdoctoral Researcher position is available at the Oregon National Primate Research Center in Beaverton, OR in the laboratory of Dr. Robert Friedman, Ph.D. The laboratory seeks a postdoctoral candidate interested in understanding cortical processes at the columnar level in monkeys performing visual cognitive tasks as well as monkeys behaving in more natural settings. We have developed wireless technology where we chamber mount a miniature camera for wide field intrinsic optical imaging, place wireless µLEDs for optogenetic stimulation, and record electrophysiologically. This approach has the potential to reveal at the mesoscale the functional circuitry both within and between cortical areas, and will have relevance for the development of targeted, column-specific (cf. Chernov et al PNAS 2018) brain-machine interfaces. The successful candidate will work with primates in a collaborative environment, collect and analyze data, prepare manuscripts for publication, and present at regional and national conferences. Applicants must hold a PhD in Neuroscience, Bioengineering, Psychology, or a closely related discipline and have a strong background in systems neuroscience. The ability to work in a team environment is essential, as are strong quantitative and programming skills (e.g. Matlab, Python, psychopy). Prior experience working with non-human primates and in the collection and analysis of neurophysiological spike train data is strongly preferred. Background in MRI is a plus. When applying interested candidates should submit a CV and or Biosketch, names of 3 references, and a statement of research interests. Salary will follow NIH guidelines and be commensurate with experience.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Oregon National Primate Research Center (ONPRC)
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2020-6425
Job Locations US-OR-Beaverton
Uncontrolled inflammation generates significant morbidity and mortality in many diseases of infectious (e.g. HIV, Mtb) and non-infectious (e.g. inflammatory bowel disease) origin. By utilizing a variety of non-human primate models of human diseases, the Estes Laboratory works to elucidate determinants of local and systemic inflammation leading to tissue pathology, disease progression, and pathogen persistence, as well as test therapeutics to modulate the immune landscape, restore immune homeostasis, and reduce pathogen tissue reservoirs.    The Estes Lab is currently recruiting a highly self-motivated and energetic postdoctoral researcher to lead a project within the new multi-center Cascade IMPAc-TB consortium, an ambitious NIH contract designed to accelerate progress in tuberculosis vaccine development. In collaboration with the Gerner Lab in Seattle, this project is designed to provide a spatial framework, via advanced in situ hybridization and immunofluorescent techniques, that will complement and synergize with other consortium projects. Additionally, this individual will also lead and collaborate on other projects within the lab, including projects to understand HIV/SIV reservoir dynamics. Background in a relevant immunology lab is required. Direct experience working on TB, HIV/SIV, non-human primate models, multiplexed in situ hybridization and protein immunofluorescence, and/or multispectral imaging is highly desirable.   Please note that this position is at OHSU's West Campus (Beaverton). Submit a resume, cover letter, and at least three references to be considered for this position.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vaccine & Gene Therapy Institute
Postion Category
Postdoctoral
HR Mission
Research
Requisition ID
2020-6311
Job Locations US-OR-Portland
This position is focused on studying the causes and progression of postpartum breast cancer using human and rodent breast tissues in a lab with a strong team-based approach to problem solving. This Postdoctoral Scholar will report to the Principal Investigator and work with a team of dedicated researchers in the areas of breast cancer progression, liver metastasis and prevention. - Preforming laboratory research; conducting experiments - Collecting, analyzing, and quantifying data - Assisting in planning and designing standard research operations. - Preparation of reports, manuscripts for publication in peer reviewed journals, submit postdoctoral fellowship grants, and support grant submissions within the lab Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental and Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-6250
Job Locations US-OR-Portland
We are seeking a highly motivated Postdoctoral Scholar to conduct research in areas of tumor immunology and tumor microenvironment, identifying cells and their mediators as critical regulators of cancer development. Specific projects will be determined by the applicants skill set and articulated research interests.   The ideal candidate for this position will be highly interactive, but capable of working independently on research focused on tumor-permissive molecular mechanisms underlying cancer-associated fibroblast function, and how these stromal mechanisms affect cell fate and function in the pancreatic epithelium.   The Postdoctoral Scholar will be the primary strategist in scientific aspects of the assigned project, and in that regard may participate in supervision of some activities of research assistants, frequently taking responsibility for expensive equipment and experiment design. It is expected that the Postdoctoral Scholar will write scientific papers, abstracts, and submit manuscripts for publication and seek out and apply for grants and additional funding to support this research.   Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental and Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-6204

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