Oregon Health & Science University

Job Listings

Click column header to sort

Here are our current job openings. Please click on the job title for more information, and apply from that page if you are interested.

Search Results Page 1 of 4

Job Locations US-OR-Portland
CEDAR funds its own research projects, expediting the process of discovery. Our research is milestone-driven to ensure that each project is fulfilling its stated goals. CEDAR is currently seeking applicants to fill multiple postdoctoral positions. CEDAR offers a unique opportunity for outstanding, driven, and creative postdoctoral fellows to perform cutting edge and high-risk research, ranging from understanding basic cancer biology to developing novel technologies to aid detection.   Duties Include: - Prepare manuscripts, and present research findings as abstracts or oral presentations. Travel may be required. - Attend weekly group meetings and 1:1 meetings to: 1) Present data and interpretation of results; 2) Troubleshoot research results; 3) Suggest next steps. - Attend research-related meetings. These could include but are not limited to: Thursday afternoon SPORE seminars, cancer biology meetings, and journal clubs. - Perform experiments utilizing appropriate lab or computational techniques with proficiency, evaluate results, and determine the next steps to complete project and present data. Think independently and solve problems. Stay on top of scientific literature and build skills to maximize project potential.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
CEDAR - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2022-14969
Job Locations US-OR-Portland
Applications are invited for a Postdoctoral Research position in the laboratory of Dr. Anupriya Agarwal at Oregon Health & Science University (OHSU) in Portland, OR.  Our laboratory focuses on identifying novel intrinsic- and extrinsic signaling pathways that are requisite for leukemia progression, clonal evolution, and drug resistance. The work will concentrate on the discovery and validation of new therapeutic targets in hematologic malignancies and the molecular characterization of signaling pathways involved in disease pathogenesis.   The position is in an interdisciplinary, collaborative, and highly translational environment in the OHSU Knight Cancer Institute and the Department of Hematology and Oncology in the OHSU School of Medicine. Highly-motivated candidates with expertise in molecular biology, hematopoiesis, cell signaling/ epigenetics, and in vivo models who are interested in a career in oncology basic/translational research will be most competitive for this position. We are looking for a highly-motivated individual who is capable and willing to make maximum use of excellent facilities and a productive environment and are interested in a career in oncology basic/translational research. They should have demonstrated their capabilities and enthusiasm by peer-reviewed publications.   Duties include: - Perform technical procedures such as electrophoresis, mammalian cell culture, DNA sub cloning and DNA purification from bacterial cultures, cell cultures and patient samples. - Small animal handling experiments (primarily mice) - Think independently and problem solve. Stay on top of the literature and build skills to maximize the projects’ potential. Attend weekly laboratory meetings and 1:1 meetings to: 1) present data and interpretation of results; 2) troubleshoot research results and 3) suggest next steps. Prepare manuscripts, present research findings as abstracts or oral presentations (travel may be required), help preparing grant applications
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Hematologic Malignancies - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-14302
Job Locations US-OR-Portland
A Postdoctoral position in Cell, Cancer or Molecular Biology is available at the Knight Cancer Institute's Center for Experimental Therapeutics (CET). Interested candidates are expected to have recently obtained their PhD and have a strong track record of publications in Cell, Cancer or Molecular biology. Job duties include performing research to understand the role of newly identified drivers in the pathogenesis of cancer so as to identify novel therapeutic targets. The translational research projects within CET leverage multi-disciplinary approach in biology, chemistry, pharmacology, molecular modeling, in vitro and patient-derived models to probe complex biological processes and to pursue new therapeutic opportunities for various diseases. As a member of multi-disciplinary team, the postdoctoral candidate will receive training in various aspects of drug discovery & development for his/her career development.   Duties Include: - Perform hands-on experiments (in vitro and in vivo) and analyze/interpret data on assigned projects - Critically evaluate relevant scientific advances and integrate this knowledge into research programs. Participate in project planning and execution - Publish research in peer-reviewed journals and present work at scientific conferences. Effectively write and/or communicate research and regulatory materials.  Attend and present at the project and group meetings and national conferences
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-13672
Job Locations US-OR-Portland
CEDAR funds its own research projects, expediting the process of discovery. Our research is milestone-driven to ensure that each project is fulfilling its stated goals. CEDAR is currently seeking applicants to fill 1-2 postdoctoral positions in the area of cancer cell biology and in particular mechanisms of cell state. CEDAR offers a unique opportunity for outstanding, driven, and creative postdoctoral fellows to perform cutting edge and high-risk research, ranging from understanding basic cancer biology to developing novel technologies to aid detection.   We are hiring a highly motivated Postdoctoral Scholar. As a CEDAR postdoc, you will work closely with Dr. Jungsun Kim and other CEDAR researchers to elucidate mechanisms that govern the establishment of cancer cell identity by utilizing a cellular reprogramming approach. Cell fate, or identity, is well-maintained through multiple chromatin states established by master transcription factors (TFs) and chromatin regulators. Dysregulation of the determination of cell identity may lead to tumorigenesis, and indeed dysregulated master TFs in cancer cells can dictate a cancer cell’s epigenetic landscape and cell state. A defined set of TFs can reprogram somatic cells into induced pluripotent stem cells (iPSCs) by rewiring the reversible epigenetic landscape of “starting” somatic cells, which is established by cell fate decisions during normal development. This led to the intriguing possibility that TF-mediated reprogramming may offer a tool to rewire and reverse aberrant epigenetic alterations in cancer cells. Indeed, we demonstrated a proof-principle of a pancreatic cancer reprogramming model that provides a human cell model for unprecedented experimental access to different stages of human pancreatic cancer. Using this system, we uncovered a regulatory network and a secreted or released protein that can discriminate early resectable stage I pancreatic cancer patients as well as all stages of PDAC from healthy controls (Kim et al., 2013 Cell Reports; Kim et al., 2017 Science Translational Medicine).     In this role you will conduct high rigorous research to define the early epigenetic changes that take place during cancer progression and will work to address the following questions; i) to what extent and how reproducibly aberrant cancer transcriptional networks can be destabilized through TF-mediated reprogramming, ii) how cells that fail reprogramming regain an aggressive tumor phenotype, and iii) what chromatin regulators maintain a cancer cell state. Addressing these questions will provide novel insight into how cancer cells establish and maintain cancer identity. Techniques you will use include next-generation sequencing (NGS) based tools such as ChIP-seq, RNA-seq, ATAC-seq, and single cell RNA-seq (Soufi et al; Cell 2015, Soufi et al; Cell 2012).   References 1. Kim J and Zaret KS et al., Science Translational Medicine 2017 Jul 12;9 (398) - Highlighted by Ray K. Nat Rev Gastroenterol Hepatol. 2017 doi: 10.1038/nrgastro.2017.111. - Highlighted by Talha Burki in Lancet Oncology News, 2017 July 20  - Featured in the CBS News, U.S.News & World Report, MSN Canada, The Japan Times, New China News, La Razón, Correio Braziliense News, Science Daily, NCI Cancer Current, and so on. -Selected as one of the Most Life-Changing Medical Breakthroughs of 2017 in Prevention magazine, 2017 Dec issue; The New Times magazine, 2017 Dec 25 2. Kim J and Zaret KS. The EMBO Journal 2015, 34: 739–747 3. Kim J and Zaret KS et al., 2013 Cell Reports 2013, 3: 2088–2099 -Highlighted in the Editor’s Choice in Science, vol 341, page 319, 2013 July 26 Featured in ESC & iPSC NEWS published by Connexon Creative, 2013 June 26 Highlighted in the Inside Life Science published by NIGMS, 2014 January 8
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-13671
Job Locations US-OR-Portland
We are looking for a post doctoral scholar interested in neural regeneration, stem cell biology, or neural cancer biology, primarily using the freshwater planarian as a model system, along with zebrafish. We use cutting edge genomic and imaging techniques to understand fundamental questions in neural regeneration and adult stem cell biology. In addition to scientific training, the postdoc will also receive personalized mentoring to advance their own career development including networking introductions, goal setting, leadership opportunities, further training in public speaking, project management, grant, and manuscript writing, and chances to review manuscripts.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Department of Pediatrics
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2022-15161
Job Locations US-OR-Portland
We are currently hiring for highly motivated postdoctoral fellows to join Dr. Thuy Ngo’s lab. The goal of Dr. Ngo’s lab is to develop and deploy technologies for analyzing cfRNA, cfDNA, extracellular vesicles (EV) and protein complexes in body fluids for applications in precisiondiagnosis and selection of therapy. Ngo lab also seeks to understand the complex environment of molecular features detected in body fluids associated disease progression and the evolution of diseases in response to treatment. Furthermore, the lab is investigating the basic mechanism of EV medicated cell-cell communication, EV's content packaging and delivery. Candidates would work in the following areas. - Cell-free RNA and cell-free DNA methylation – Design experiments and perform sample preparation to sequence circulating RNA (mRNA, miRNA, transposable elements, circular RNA and microbiome) and DNA methylation from patient’s blood samples. Use existing tools and develop new methods to identify biomarkers, perform classification and prediction modelling, and analyze biological pathways associated with patient samples during cancer progression and under treatment. - Extracellular vesicles- Design experiments and perform sample preparation to analyze protein and RNA cargos of extracellular vesicles in body fluids and spent culture media. Investigate mechanism of EV biogenesis and delivery. - Developing new technologies for screening and measuring with low background, high sensitivity, high resolution and wide dynamic range to profile proteins and RNA cargos of EV and protein complexes, to characterize them physically and to measure them at both single complex level and at high a throughput manner.  - Transcriptome/Epigenome–Modeling and analyzing next-generation sequencing datasets that measure the transcriptome and the epigenome of cell-free RNA, cell-free DNA and extracellular vesicles in blood. Performing analysis of existing genomics data of cancerous cells to aid the design of cell-free RNA and cell-free DNA methylation assays. The successful candidate will use both existing tools and develop their own computational methods to analyze such datasets for characterization of healthy and cancerous patient populations. - Machine Learning/Statistics/Multiomics – Developing machine learning methods and statistical models for feature selection, classification, anomaly detection, time series analysis, and multiomics data integration.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-13093
Job Locations US-OR-Portland
This position is for a Computational Biology and/or Bioinformatics Postdoctoral Scholar who will have the opportunity to design and lead research projects for prioritizing therapies, selecting combination therapies, and evaluating resistance pathways in breast, ovarian, and endometrial cancers. Specific duties include:   - Applied computational research project(s) in precision oncology of breast and gynecological cancers. - Maintaining reproducible scripts, code, and interactive notebooks as needed for research projects, including ongoing methods documentation (i.e. maintaining a dry lab notebook or GitHub code repositories). - Participating in lab meetings, making contributions and submitting research for publication, submitting applications for research funding, presenting research at seminars, poster sessions and conferences.   Salary for this position aligns with the NIH scale: https://www.ohsu.edu/postdoctoral-affairs/salary
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Knight Cancer Systems Biology - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-11009
Job Locations US-OR-Portland
We are currently hiring for 1-2 highly motivated fellows with expertise in Cancer Biology to work in the following areas with a particular focus on Leukemia. Individuals with a strong background in Cancer Biology, Leukemia Biology or other related Molecular Biology discipline are encouraged to apply. Candidates would work with a range of CEDAR and OHSU scientists and clinicians conducting leukemia research. Cancer Epigenetics. Dysregulation or mutation of epigenetic regulators is an early event in leukemia development, yet the underlying mechanisms are poorly understood. Projects in this area will involve genomic and functional studies characterizing the epigenetic mechanisms of cancer using single cell and low input epigenetic methods in cell lines, genetically engineered mouse models and primary patient samples. Hematopoietic Stem Cell Biology. The earliest events in leukemia formation occur in the hematopoietic stem cell, leading to clonal expansion and facilitating the acquisition of subsequent transformative mutations. Projects in this area will investigate the impact of early leukemic mutations on stem cell function using both human and murine systems. Single Cell Multiomics Methodology Development. Early precancerous cells are subclonal populations surrounded by a large number of normal cells. Single cell sequencing methodologies are therefore well poised to interrogate these rare pre-malignant cells. A key component of this process will be linking multiple types of data to the same single cell including genotype, transcriptome, epigenome and proteome. Projects in this space will work to develop methodologies. Target Identification and Drug Development for Early Stage Blood Cancers. Specific mutations and mutation profiles are associated with an exceedingly high risk of progression from myelodysplastic syndrome and myeloproliferative neoplasms to acute myeloid leukemia. These include key epigenetic regulators and splicing factors. These mutations represent possible targets for early intervention. Projects in this area will identify key pathway dependencies produced by these mutations that are potentially targetable. These studies will use a variety of methodology including genome wide CRISPR screening, protein-protein interaction studies and a variety of molecular and cell biology techniques to validate targets.   Duties Include: - Prepare manuscripts, and present research findings as abstracts or oral presentations (travel may be required) - Attend weekly group meetings and 1:1 meetings to: 1) present data and interpretation of results; 2) troubleshoot research results and 3) suggest next steps - Attend research related meetings including but not limited to Thursday PM SPORE seminars, Cancer Biology meetings, journal clubs - Perform experiments utilizing appropriate lab or computational techniques with proficiency, evaluate results, and determine the next steps to complete project and present data.  Think independently and problem solve. Stay on top of the literature and build skills to maximize the projects’ potential. - Duties as assigned
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
CEDAR - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-7938
Job Locations US-OR-Portland
We are currently hiring for 1-2 highly motivated fellows with expertise in Computational Biology to work in the following areas. Candidate would work with CEDAR and OHSU scientists including Gurkan Yardimci, Hisham Mohammed, Andrew Adey and Xiaolin Nan initially and with increasing collaborations over time: - Machine Learning/Statistics– Developing machine learning methods and/or statistical models to study the organization of the epigenome and three dimensional structure of the genome using cutting edge genomics and super resolution microscopy datasets.  Developed algorithms will be used to deeply characterize cell populations and identify features that are indicative of cell state. Techniques such as (but not limited to) dimensionality reduction, clustering, and predictive modeling will be utilized. - Genomics/single cell genomics Modeling and analyzing next-generation sequencing datasets that measure the transcriptome and the epigenome, with an emphasis on the single-cell variants, such as single cell RNA-seq and single cell ATAC-seq. The successful candidate will use both existing tools and develop their own computational methods to analyze such datasets for characterization of healthy and cancerous cell populations. - Multiomics– Developing computational methods for the analysis of single-cell multiomics technologies that are able to characterize multiple “omes” of a single cell concurrently, such as the epigenome and the transcriptome (see references below). These methods will be utilized for deep characterization of healthy and cancerous cells and investigate the links between the transcriptome, the epigenome and 3D conformation of chromatin. - Imaging –Performing analysis of existing genomics data of cancerous cells to aid the design of super high resolution microscopy experiments for imaging the chromatin organization of cancerous cells. The successful candidate will have the opportunity to analyze cutting edge super high resolution microscopy experiments and develop computational methods for joint analysis of genomics and imaging data.  Select references: - https://www.nature.com/articles/s41586-019-1825-8 https://www.nature.com/articles/nbt.4112 - https://science.sciencemag.org/content/361/6409/1380 - https://www.nature.com/articles/s41467-020-18181-6 - https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008173 Duties Include: - Prepare manuscripts, and present research findings as abstracts or oral presentations (travel may be required) - Attend weekly group meetings and 1:1 meetings to: 1) present data and interpretation of results; 2) troubleshoot research results and 3) suggest next steps - Attend research related meetings including but not limited to Thursday PM SPORE seminars, Cancer Biology meetings, journal clubs - Perform experiments utilizing appropriate lab or computational techniques with proficiency, evaluate results, and determine the next steps to complete project and present data.  Think independently and problem solve. Stay on top of the literature and build skills to maximize the projects’ potential. - Duties as assigned
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
CEDAR - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-7465
Job Locations US-OR-Portland
The Center for Experimental Therapeutics at the Knight Cancer Institute is seeking Postdocs to join the Chemical Biology & Drug Discovery laboratory. Expertise in biology (cell, molecular, cancer) and/or immunology is an essential requirement of this position to drive the work on a project associated with tumor heterogeneity, subclonal evolution and response to drug therapy, to achieve project goals. Ideal candidates should be intellectually curious, well-organized and well-versed in constructive problem solving. Experience with cell culture and mouse modeling is preferred. The selected candidate will participate in establishing project goals, defining short and long-term scientific strategies, and contribute to the generation of project-related documents and presentations. They will collaborate with functional and technical experts to facilitate scientific achievement, and will be responsible for compliance with applicable Corporate and Divisional Policies and procedures. They will demonstrate a high degree of responsibility in maintaining scientific standards, and safe laboratory practices for the work unit.   Duties Include: - Conceive and execute disease biology focused research and development efforts to achieve project and program goals. S/he will perform routine and complex laboratory procedures throughout training period in the field of cancer biology. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Assist in preparation of grant proposals. Responsible for designing experiments, assembling data for publications and presentations as author or co-author. - Critically evaluate relevant scientific advances and integrate this knowledge into research programs. Maintain a high level of productivity in the laboratory setting. Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise. - Publish research in peer-reviewed journals and present work at scientific conferences. Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program. Effectively write and/or communicate research and regulatory materials. - Build strong relationships with peers and cross functionally with partners outside of teams to enable higher performance.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Center for Experimental Therapeutics - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-7339
Job Locations US-OR-Portland
- Review and analysis of prior work on the reactivity if particulate activated carbon, including electrochemistry using “powder electrodes”. - Performing electrochemical experiments using activated carbon-modified electrodes. - Preparation and operation of batch and column reactors for determining the rates and products of chemical reactions in environmental media. - Numerical modeling of contaminant reactions in the pores space of packed beds containing activated carbon. - Writing of manuscripts for peer-reviewed journals - Presentation of results at professional society meetings or workshops organized by the sponsor. - Drafting technical reports for the project sponsor. - Operation and maintenance of anaerobic glove boxes, updating laboratory supply inventories, documenting standard operating procedures, and maintaining laboratory safety protocols. - This description is not intended to be all-inclusive, and the incumbent will be required to assume additional duties as assigned.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
OHSU-PSU School of Public Health
Postion Category
Postdoctoral
HR Mission
Academics
Requisition ID
2021-14915
Job Locations US-OR-Portland
Oregon Health & Science University is recruiting for a postdoctoral fellow who will serve as the project leader using human electrophysiology to decode cortical functions and measure epilepsy activity.  Experiments are conducted in human subjects with novel ultra high-density biointerfaces during craniotomies as well as with subacutely implanted clinical stereoencephalography electrodes and subdural grids. Facility with programming in Matlab and/or Python is required.  Experience with cognitive network research, neural signal processing, big data processing/machine learning techniques, and/or medical image processing would be beneficial. This position would be appropriate for somebody with previous training or work experience in cognitive neurosciences, computational neuroscience, computer science, electrical and computer engineering, physics, mathematics, neural engineering and/or neuroscience.    Duties of the position include: - Provide research coordination and project management for multi-year research projects, and assist in planning design, procedures and executing research studies - Responsible for training, mentoring, and supervising research assistants, students, and junior staff - Preparation of written reports, documents, correspondence, and peer-reviewed publications Work will be conducted under the direction of Dr. Ahmed M. Raslan (PI). Salary scale follows the current NIH Kirschstein-NRSA stipend levels (commensurate with years of experience).
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Neurological Surgery
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2022-15075
Job Locations US-OR-Portland
Responsibilities include: - Plans, conducts, and completes laboratory experiments. Performs primary molecular genetic techniques including PCR, DNA and RNA assays, Western blot, Northern and Southern blot analysis, protein purification, enzymatic assays, fluorescent and light microscopy, mouse handling and tissue collection and analysis including IHC staining. - Collects, records organizes and verified the accuracy of data. Conducts literature search and summarizes information in an appropriate format for a particular study; Documents and interprets results of experiments and reports to principal investigator. Presents data at lab meetings and participates in journal club and research group meetings. - Assists in the daily operation of the lab including hazardous waste disposal, sterilization of equipment, general lab equipment maintenance, and preparation of media and buffers. Operates a variety of instruments and scientific equipment. Independent design and implementation of experiments and assays as well as assuring compliance with established safety procedures - Supervisory responsibilities over lab technicians and students as well as the general management of the lab The appointee shall provide services as assigned by the supervisor in furtherance of the university’s missions and goals of teaching, research, patient care, outreach and public service. There will be cell biology, biochemistry and animal work involved.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Molecular & Medical Genetics
Postion Category
Research
HR Mission
School of Medicine
Requisition ID
2019-1645
Job Locations US-OR-Portland
A successful candidate will have the opportunity to work closely with Dr. Carolyn Schutt Ibsen and other CEDAR researchers to develop key technology platforms involving stimuli-responsive hydrogel scaffolds for 3D culture, drug delivery nanomaterials, and 3D bioprinting with applications in tissue engineering and modeling tumor progression.   We are currently hiring for 1-2 highly motivated fellows with expertise in Biomaterials to work in the following general areas: - Stimuli-responsive hydrogel scaffolds for 3D cell culture– developing new “smart” hydrogel-based materials for applications in tumor modeling and tissue engineering. This work will explore the use physical-stimuli responsive biomaterial scaffolds that enable spatiotemporal control of cue delivery (Gelmi and Schutt, 2021; Nele, Schutt, et al. 2020). Includes modification and functionalization of hydrogel polymer systems, cell culture within 3D engineered scaffolds and use of imaging and characterization techniques including confocal microscopy and immunofluorescence imaging. This position will utilize high-end instrumentation with access to the OHSU Advanced Light Microscopy Core and Multiscale Microscopy Core. - Drug and gene delivery nanomaterial engineering– fabrication and functionalization of nano and micro-particles, including external stimuli-responsive particles (Schutt et al. 2017, Schutt et al. 2015) for delivery of small molecule, protein or nucleic acid cargoes, and characterization via techniques including NTA, DLS/zetasizer, super-resolution microscopy, and electron microscopy via state-of-the-art instrumentation. - 3D bioprinting of complex tissue constructs– development of complex multi-typic bioprinted systems for applications in tumor modeling and tissue engineering. Includes development and modification of bioinks, printing parameters and techniques (e.g. FRESH bioprinting) and culture protocols as well as advanced imaging and characterization techniques   References: - Gelmi A and Schutt CE. Stimuli-Responsive Biomaterials: Scaffolds for Stem Cell Control. Advanced Healthcare Materials. 2021 Jan; 10(1):e2001125. - Nele V, Schutt CE, Wojciechowski JP, Kit-Anan W, Doutch JJ, Armstrong JPK, Stevens MM. Ultrasound-Triggered Enzymatic Gelation. Advanced Materials. 2020 Feb; 32(7):e1905914. - Schutt CE, Ibsen S, Zahavy E, Aryal S, Kuo S, Esener S, Berns M, Esener S. Drug Delivery Nanoparticles with Locally Tunable Toxicity Made Entirely from a Light-Activatable Prodrug of Doxorubicin. Pharmaceutical Research. 2017 Oct; 34(10):2025-2035. - Schutt CE, Ibsen SD, Benchimol MJ, Hsu MJ, Esener SC. Manipulating nanoscale features on the surface of dye-loaded microbubbles to increase their ultrasound-modulated fluorescence output. Small. 2014 Aug 27;10(16):3316-24.   OHSU Knight Cancer Institute Blog Highlight: https://blogs.ohsu.edu/cancertranslated/2021/01/28/engineering-models-of-early-cancer-qa-with-carolyn-schutt-ibsen/   Duties Include: - Prepare manuscripts, and present research findings as abstracts or oral presentations (travel may be required) - Attend weekly group meetings and 1:1 meetings to: 1) present data and interpretation of results; 2) troubleshoot research results and 3) suggest next steps - Attend research related meetings including but not limited to Thursday PM SPORE seminars, Cancer Biology meetings, journal clubs - Perform experiments utilizing appropriate lab or computational techniques with proficiency, evaluate results, and determine the next steps to complete project and present data.  Think independently and problem solve. Stay on top of the literature and build skills to maximize the projects’ potential. - Duties as assigned
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
CEDAR - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-14405
Job Locations US-OR-Portland
- Plan and perform experiments related to the research goals of the lab - Interpret experiments - Write preliminary drafts of manuscripts - Attend and present at lab meetings and at local/national/international meetings Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental and Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-9454
Job Locations US-OR-Portland
We are currently hiring for 1-2 highly motivated fellows with expertise in Biochemisty to work in the following areas: - Functionalized polymers– making new specially-functionalized polymers for ongoing and anticipated projects; including hydrogels, modified hydrogels, specially-functionalized hydrogels, 3D functionalized specialty polymers for cellular analysis (for example via expansion microscopy), basically chemical enablement of  multi-dimensional approaches to analysis of biological samples at the interfaces of biological, chemical and engineering technologies - Organic synthesis of small molecules– biological probes such as fluorescent dyes, affinity reagents, especially probes that are enabled with linkers and reactive chemical groups for bioconjugation, drug molecules or drug-like molecules, new linkers with designed properties such as solubility and desired conformational properties (rigidity or flexibility) and reversible crosslinkers cleaved by light, chemical or biochemical reagents - Chemical reaction of biomolecules– e.g., bioconjugation of chemical and biochemical probes to biological molecules such as DNA, RNA and proteins; attachment of biological molecules to surfaces using functionalized linkers, attachment of biological molecules to polymers using functionalized linkers; Polymer-oligo DNA or RNA cross linking or manipulation - Nanoparticle synthesis and surface modification– preparation of standard and new types of nanoparticles, surface functionalization of nanoparticles to provide desired properties of nanoparticles The OHSU Fellowship for Diversity in Research seeks to address the need for increased representation of minoritized races/ethnicities in STEM at the postdoctoral level. Eligible candidates are encouraged to apply. Visit www.ohsu.edu/ofdir for more information. Recent references: - https://www.nature.com/articles/s41467-020-18181-6 - https://www.eurekalert.org/pub_releases/2018-09/uoo-occ091718.php#:~:text=%2D%20Sept.,made%20of%20carbon%20and%20hydrogen - https://pubs.acs.org/doi/10.1021/acscentsci.8b00346 - Montoya Mira J, Wu L, Sabuncu S, SapreA, Civitci F, Ibsen S, Esener S, Yildirim A. "Gas-Stabilizing sub-100 nm Mesoporous Silica Nanoparticles for Ultrasound Theranostics”. ACS Omega, 2020. (accepted) Duties Include: - Prepare manuscripts, and present research findings as abstracts or oral presentations (travel may be required) - Attend weekly group meetings and 1:1 meetings to: 1) present data and interpretation of results; 2) troubleshoot research results and 3) suggest next steps - Attend research related meetings including but not limited to Thursday PM SPORE seminars, Cancer Biology meetings, journal clubs - Perform experiments utilizing appropriate lab or computational techniques with proficiency, evaluate results, and determine the next steps to complete project and present data.  Think independently and problem solve. Stay on top of the literature and build skills to maximize the projects’ potential. - Duties as assigned
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
CEDAR - Knight Cancer Institute
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2020-6379
Job Locations US-OR-Beaverton
Oregon Health & Science University is always looking for qualified postdoctoral scholars to fulfill its mission of conducting leading edge research into new cures, new standards of care, and a better understanding of the basic science that drives biomedical discovery.   The postdoctoral experience provides individuals who have recently completed a doctoral degree with a full-time program of advanced academic preparation and research training under the guidance of a supervising faculty mentor.  Postdoctoral appointments are temporary by nature and are designed to develop the postdoctoral scholar as an independent scientist and to enhance their professional skills for academic and non-academic careers.   We are a large nonhuman primate (NHP) research program at the Vaccine and Gene Therapy Institute (VGTI) focused on 1) the collaborative development of cytomegalovirus (CMV)-based vaccine vectors for prevention and treatment of infectious and neoplastic diseases of global importance, including (in rough order of emphasis) HIV/AIDS, tuberculosis, malaria, Hepatitis B, influenza and prostate cancer, and 2) the development of novel approaches (both vaccine and non-vaccine) to cure established HIV/SIV infection. To facilitate our goals the research group is comprised of faculty level Program Managers as well as an Administrative Support Group which includes a Laboratory Manager, Project Administrator (budget and compliance) and support staff for administrative duties, supply, procurement, reagent and inventory management, as well as a dedicated Flow Cytometry Group which supports the research focuses described below. Of note, our group interacts on a daily basis with the NHP Pathology Lab and the Infectious Disease Resource (IDR), and closely collaborates with other VGTI labs.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vaccine and Gene Therapy Institute
Postion Category
Research
HR Mission
Research
Requisition ID
2021-14814
Job Locations US-OR-Beaverton
Oregon Health & Science University is always looking for qualified postdoctoral scholars to fulfill its mission of conducting leading edge research into new cures, new standards of care, and a better understanding of the basic science that drives biomedical discovery.   The postdoctoral experience provides individuals who have recently completed a doctoral degree with a full-time program of advanced academic preparation and research training under the guidance of a supervising faculty mentor.  Postdoctoral appointments are temporary by nature and are designed to develop the postdoctoral scholar as an independent scientist and to enhance their professional skills for academic and non-academic careers.   A Postdoctoral Fellowship position is available for NIH-funded research into molecular aspects of human cytomegalovirus infection and latency. The lab focuses on virus-host interactions using state-of-the-art assays in human progenitor cells. The lab has special interest in the role of viral miRNAs in modulating HCMV latency and reactivation. Preferred technical skills include molecular cloning, cell culture and standard molecular biology techniques (immunoblotting, RNA isolation and analysis, microscopy, flow cytometry). Candidates must be well organized, technically proficient, critically minded and able to work independently as well as collaboratively.   The lab is located at the Vaccine and Gene Therapy Institute (VGTI) in Beaverton, OR. VGTI houses a multidisciplinary team of scientists that span the continuum between basic and clinical research. VGTI offers access to state-of-the-art equipment and Core facilities as well as easy access to the Oregon wilderness.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Vaccine and Gene Therapy Institute
Postion Category
Research
HR Mission
Research
Requisition ID
2021-14632
Job Locations US-OR-Portland
A Postdoctoral Scholar position with a bioinformatics/computational, experimental, or dual focus is available immediately in the laboratory of Dr. Brian J. O’Roak, Department of Molecular and Medical Genetics at Oregon Health & Science University (OHSU) for highly motivated individuals. Highlights of Dr. O’Roak’s past research successes include: pioneering trio-based exome sequencing in simplex autism and developing new technologies for rapid and economical targeted resequencing.   We are building on this experience by forming a strong and diverse research group focused on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular diagnosis, functional dissection of pathways, and targeted therapeutics for neurodevelopmental and related disorders. This work has the potential to dramatically improve the lives of individuals affected with these currently untreatable disorders through early intervention and biologically based personal therapies.   Areas of interest include: genomics, single-cell genomics, modeling of neurodevelopmental disorders in stem cell (iPSC) and animal systems, massively parallel functional assays, and bioinformatics.   In particular, there is an immediate need for a fellow with next-generation sequence analysis experience to lead a project exploring the role of germline mutations and somatic mosaicism in autism and other neurodevelopmental disorders (e.g. neural tube detects), for which long-term funding currently exists. This would build on our work recently published in the AJHG (see Krupp et al. 2017).   Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Molecular and Medical Genetics
Postion Category
Research
HR Mission
School of Medicine
Requisition ID
2019-1786
Job Locations US-OR-Portland
The Postdoctoral Scholar will have the opportunity to design and lead research projects for prioritizing therapies, selecting combination therapies, and evaluating resistance pathways in breast, ovarian, and endometrial cancers. Duties include: - Research project(s) in adaptive response to therapy in cancer. - Generally maintaining reproducible notebooks as needed for research projects. Includes ongoing methods of documentation, i.e. maintaining a dry lab notebook or GitHub code repositories. - Participating in lab meetings, making contributions and submitting research for publication, submitting applications for research funding, presenting research at seminars, poster sessions and conferences. Salary for this position aligns with the NIH Scale.
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Cell, Developmental & Cancer Biology
Postion Category
Postdoctoral
HR Mission
School of Medicine
Requisition ID
2021-11168

Use this form to perform another job search

The system cannot access your location for 1 of 2 reasons:
  1. Permission to access your location has been denied. Please reload the page and allow the browser to access your location information.
  2. Your location information has yet to be received. Please wait a moment then hit [Search] again.