A fully-funded postdoctoral researcher position is available in the laboratory of Dr. Bret Pearson at the Pape Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR. We are currently building our team and looking for a Postdoctoral Fellow interested in studying the molecular connections between stem cell biology, neural injury, and neural cancer biology, primarily using the unique combination of model systems: freshwater planarians and zebrafish (https://www.bretpearsonlab.org). We use cutting edge genomic and imaging techniques to understand fundamental questions in adult stem cell biology in...
The Department of Pediatrics is recruiting for a Post Doctoral Scholar position. The position is in the laboratory of Dr. Stephen Back studying cellular and molecular mechanisms of human white matter injury related to aging and cognitive decline. The project utilizes a unique collection of human autopsy brains from subjects identified with vascular brain injury, Alzheimers Disease and MRI-defined white matter hyperintensity signal abnormalities (see: Annals of Neurology 70:465-476, 2011; Journal of Neuropathology and Experimental Neurology, 75(6):539-554, 2016; Annals of Neurology 83:142-152, 2018)
This position requires a Ph. D. in bioengineering, chemical engineering, materials science, nanotechnology, or a relevant field. This position will work on Dr. Adem Yildirim’s research projects. They should also have the potential to both lead and participate in projects in Dr. Yildirim’s group. This position requires a strong track record of scholarly activity, including high-quality peer-reviewed publications or other translational research activities. Experience in nanomaterial synthesis and characterization, immunotherapy, and/or small animal tumor models are required. A record of collaborative research, or the potential for collaborative research, is preferred for this position....
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Division of Oncological Sciences - Knight Cancer Institute
- Participate in lab work and research projects as assigned.
- Develop innovative research projects and tools.
- Prepare results for publications, presentations, database, and grant submissions.
- Attend and present technical status reports at group meetings.
- Assists in the daily operation of the lab including hazardous waste disposal, sterilization of equipment, cleaning glassware, general servicing of equipment and ordering lab supplies, and preparation of media and buffers.
- Other duties as assigned.
Strong preference will be given to candidates with experience engineering complex 3D tissue models, organ-on-chip systems, cancer microenvironment models, bone biology, or biofabrication. Additional preferred expertise includes immune cell incorporation into engineered tissues, macrophage/osteoclast biology, mouse-derived immune or tumor models, neurobiology, neuron co-culture, innervated tissue models, and/or spatial omics.
An ideal candidate will have a strong record of publications, a proven record of independence, and the ability to work effectively with the...
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Harvesting cochlear tissues, and immunohistochemistry, confocal imaging, PCR and RT-PCR analysis requiring mastery of complex principles and practices.
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Measurement of blood flow with intravital fluorescence microscopy based on lab established protocol and the measurement of auditory function with auditory brainstem response.
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Animal husbandry to maintain mouse colonies, and genotyping of transgenic mice.
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Administration of agents to animals through fine animal surgery (e.g. semicircular canal surgery)
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Analysis and reporting of data.
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Write scientific papers and present...
- Primary Research (including planning, granting, execution, analysis, publication).
- Maintain laboratory compliance documentation for human, animal, biological and radiological work.
- Be familiar with lab safety infrastructure and ensure compliance with all safety regulations.
- Interact with biosafety, chemical safety, and safety officers on behalf of the Principal Investigator.
- Generate data and research analysis for investigator's use in preparation of technical reports and publications.
- Assist the PI with manuscript preparation and grant applications.
- Present, or assist in the presentation of, research projects at retreats, seminars, conferences and other OHSU or public venues.
- Providing training to...
To perform, collect and analyze research procedures in all aspects of laboratory setting and ensure accuracy and progression of research projects, including but not limit to:
- Collect and analyze research data
- Keep accurate details of experimental procedures and original data
- Prepare research summaries, abstracts, manuscripts
- Develops and document standardized lab protocols, and assist with training of...
The postdoctoral scholar will serve as a scientific leader on assigned projects and will be expected to independently design, execute, analyze, and interpret experiments. The candidate will participate in collaborative studies within the laboratory as well as with researchers across OHSU and the Knight Cancer Institute. Opportunities for career development, scientific networking, and interdisciplinary collaboration are integral components of this position.
- Design and conduct independent research projects related to dendritic cell function in skin homeostasis and anti-tumor immunity.
- Analyze and interpret experimental data and present findings at laboratory meetings, institutional seminars, and scientific conferences.
- Prepare manuscripts for...
- Supports basic day-to-day functions of the lab, including assisting with ordering supplies. Oversees and assists with training of new or temporary students and other personnel. Attends all laboratory research and division/department meetings.
- Independently sets up and carries out cell culture experiments with cell lines and primary human skin cells. Analyzes results using techniques listed in position summary. Independently prepares, labels, and images slides using stains, immunolabeling, and in situ hybridization with both chromogens and fluorophores. Processes human blood and tissue to produce single-cell suspensions, single-nucleus suspensions, peripheral blood mononuclear cells, serum, and plasma. Prepares cDNA libraries for sequencing from fixed and frozen...
- Conduct statistical analyses using longitudinal and administrative datasets. Implement methods to address missing data, attrition methods, and complex sampling.
- Lead and contribute to manuscript manuscripts, reports, and presentations for academic, policy, and community audiences.
- Contribute to grant development and writing.
- Conduct quasi-experimental analyses of the impact of economic policies and programs on maternal and infant health.
- Collaborate with community and program partners to support interpretation and dissemination of findings.
- Present findings at team meetings, conferences, and stakeholder convenings.
- Support mentoring of graduate students or research staff.
- Design and program experiments in C++ and/or MATLAB.
- Conduct experiments with human subjects with normal-hearing, hearing aids, and cochlear implants.
- Preparation of grant or fellowship applications.
- Preparation of publications describing research results and presentation of those results at scientific meetings.
- Mentor students and research staff in the lab.
The Department of Neurology at Oregon Health & Science University seeks a post-doctoral fellow in clinical neuropsychology. This position is a two-year fellowship designed to meet INS-Division 40, Houston Conference Guidelines, and ABPP preparation guidelines.
Clinical opportunities are in the outpatient Neurology clinic, OHSU Deep Brain Stimulation Clinic, the Oregon Parkinson’s Center, and the OHSU Layton Aging and Alzheimer’s Disease Center....
The CET is seeking a Postdoc to join the Chemical Biology & Drug Discovery laboratory. Expertise in synthetic organic chemistry is essential for this position to drive the SAR optimization cycle and achieve project goals. The selected candidate will participate in establishing project goals, defining short and long-term scientific strategies, and contribute to the generation of project-related documents and presentations. They will collaborate with functional and technical experts to facilitate scientific achievement, and will be responsible for compliance with applicable Corporate and Divisional Policies and procedures. They will demonstrate a high degree of responsibility in maintaining...
Posting FTE
1.00
Position Type
Regular Full-Time
Posting Department
Center for Experimental Therapeutics - Knight Cancer Institute
Research design and conduct
- Under faculty mentorship, design and perform experiments in informatics areas of study
Data analysis and record keeping
- Perform complex data analysis, normalization and interpretation on experimental/performance results generated using functional informatics and relevant techniques/protocols.
- Use computer software to input and manage data for future analysis.
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Research design & conduct
- Under the mentorship of faculty in DICE and the Casey Eye Institute, design and perform quantitative and qualitative research studies related to early detection and intervention for eye diseases such as glaucoma, diabetic retinopathy, and age-related macular degeneration in primary care settings.
- Conduct data analysis by working with internal and external evaluation, informatics, and healthcare teams.
Dissemination in collaboration with team members
- Processing and analyzing CRISPR screening data, including data curation, normalization, quality control, hit identification, and downstream statistical analysis using Python, R, and other relevant software tools.
- Integrating CRISPR perturbation data with transcriptomics, metabolomics, proteomics, and other omics datasets to identify metabolic pathway alterations, gene dependencies, and functional mechanisms.
- Assisting in the development and implementation of robust computational pipelines, algorithms, and reproducible workflows for analyzing CRISPR-based functional genomics data and metabolic phenotypes.
- Producing analytical summaries, reports, and data visualizations of CRISPR screening and multi-omics results, including statistical analyses,...
This position is full-time and the responsibilities are to conduct research exploring the structural and biophysical mechanisms of synaptic transmission by elucidating the structures of native neurotransmitter receptors or transporters, and their synapses, or elements of the auditory transduction complex, by single particle cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) studies, in combination with complementary biochemical experiments.
- Planning, executing, and analyzing experiments for independent research project(s) using biochemical methods and single particle and tomographic cryo-EM methods to elucidate the structure(s) of the target molecule(s) and their organization.
- Manuscript preparation for individual projects and assisting other...
The candidate will design and execute independent, hands-on experiments; maintain rigorous laboratory documentation; collect, organize, analyze, and interpret complex datasets; and prepare manuscripts for publication. Additional responsibilities include presenting findings at seminars and scientific conferences, developing experimental protocols, contributing to grant applications and progress reports, and preparing technical reports. The position also involves training and mentoring junior personnel. The role requires scientific independence, strong analytical skills, flexibility, and demonstrated expertise in developmental and stem cell biology.
Technical Research Responsibilities
- Independently perform somatic cell nuclear transfer...
The candidate will design and execute independent, hands-on experiments; maintain rigorous laboratory documentation; collect, organize, analyze, and interpret complex datasets; and prepare manuscripts for publication. Additional responsibilities include presenting findings at seminars and scientific conferences, developing experimental protocols, contributing to grant applications and progress reports, and preparing technical reports. The position also involves training and mentoring junior personnel. The role requires scientific independence, strong analytical skills, flexibility, and demonstrated expertise in developmental and stem cell biology.
Technical Research Responsibilities
Independently conduct cutting-edge research focused on the...