The goal of the Wolf lab is to understand synaptic plasticity in the nucleus accumbens and related circuits that underlies this persistent vulnerability. We use the incubation of drug craving model in which cue-induced drug craving in rats progressively intensifies (incubates) over the first weeks of abstinence from drug self-administration and then remains high for months. This model has translational relevance because incubation of craving also occurs in humans. Our experiments involve electrophysiology, chemogenetics, fiber photometry, translating ribosome affinity purification, and behavioral assessments.

 

The lab is seeking a Postdoctoral Scholar for a full-time program of advanced academic preparation and research training on NIH-funded projects under the guidance of the PI and senior laboratory personnel. Training will include intravenous drug self-administration and electrophysiology.

• Planning and designing research experiments; establishing priorities and schedules; obtaining cost estimates.
• Data collection, processing and analysis, including statistical analyses, presentation of project results, and producing written documents (abstracts, manuscripts) on the result of analyses. Includes contributing to preparation of grant proposals to NIH and private foundations.
• Training new staff, graduate students, and student volunteers.
• Other duties as assigned.

• Ph.D. in Neuroscience, Psychology or related field.
• 5 years of experience in neuroscience wet lab techniques including rodent use.
• Experimental design, statistical analyses, rodent handling and surgery; ability to troubleshoot and work independently once trained.

• Background in addiction research.

• Experience with whole cell patch clamp recordings or other electrophysiological techniques.

Monday - Friday, up to 8 hours per day, some weekend work may be required.

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