Applicants are invited to apply for a Postdoctoral Research position in the laboratory of Dr. Angelina Vaseva within the Division of Pediatric Hematology and Oncology, Department of Pediatrics. The work will be focused on pediatric solid tumors with hyperactive RAS signaling such as RAS-driven rhabdomyosarcoma and NF1-associated malignant peripheral nerve sheath tumor. The candidate will explore novel approaches to target RAS and RAS signaling in these cancers with the goal to define directions for novel therapies. The work involves combination of omics (RNAseq, DNAseq, proteomics) and in vivo and in vitro experimental approaches such as synthetic lethal screens, drug response assays, molecular biology, biochemistry and use of patient-derived xenograft models in mice. Ideal candidates will be independent, motivated and hard-working. They are expected to work closely with the PIs and demonstrate excellent communication and intrapersonal skills. Qualifications include significant training in Cancer biology, protein biochemistry, cell culture techniques and mice handling. In addition, experience with bioinformatics, computational biology, or a related discipline will be considered a strength. Responsibilities include performing experiments, data analysis, reports, and manuscript preparation. Dr. Vaseva is committed to trainees¿ career development and will provide opportunities for the successful candidate to compete for fellowships, high-profile publications, and academic awards.

• PhD degree in science or technology
• Ability to operate complex scientific equipment
• In depth knowledge of specific areas of responsibility
• Ability to work with and supervise junior staff
• Ability to prioritize multiple tasks at one time
• Must have excellent communication, analytical and organizational skills: both written and verbal.
• Ability to work independently and as part of a team while being collaborative in resolving problems.
• Must be proficient with computers running Windows and PC applications e.g. MS Excel, Oracle, Access, Word and PowerPoint).
• Must have demonstrated excellent customer service skills both on the phone and in person.
• Must possess energy and drive to coordinate multiple projects simultaneously.
• Ability to use tact and diplomacy to maintain effective working relationships

• 4 or more years of related laboratory experience
• Molecular Biology and Protein Expression
• In vivo studies in the murine model
• Pluripotent stem cell culture experience, including generation of new iPS lines
• Single cell sequencing experience

Location of employment is in molecular biology research lab. Work involves possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids, presence of carcinogenic substances and human and animal tissues and fluids, including whole animals.

 

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Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.