Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are composed of biologists, chemists, biomedical engineers, computational biologists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.

 

CEDAR is committed to increasing the diversity of the campus community. We at CEDAR are dedicated to promoting inclusion and multiculturalism to build a successful organization by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires unproven, out-of-the-box thinking. Our research is milestone driven to ensure that each project is fulfilling its stated goals.

 

Every Knight Cancer employee is expected to embody our guiding principles:

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

CEDAR funds its own research projects, expediting the process of discovery. Our research is milestone-driven to ensure that each project is fulfilling its stated goals. CEDAR offers a unique opportunity for outstanding, driven, and creative postdoctoral fellows to perform cutting edge and high-risk research, ranging from understanding basic cancer biology to developing novel technologies to aid detection. Our focus on early detection requires novel approaches to reliably identify small/rare signals in diverse data types, with an emphasis on minimally invasive sampling techniques.

 

We are currently hiring for a highly motivated fellow with expertise in Cancer Biology to work in the following areas. Candidate would primarily work with Dr. Ece Eksi, Assistant Professor in the Division of Oncological Sciences with affiliations in the Biomedical Engineering and Cell, Development and Cancer Biology departments.

• Spatial imaging of the prostate tumor microenvironment – Performing multiplex imaging on patient samples acquired from prostate and pancreatic cancer patients to analyze intercellular interactions across cells in the microenvironment. The successful candidate will have the opportunity to learn existing experimental protocols and computational pipelines to generate and analyze single-cell, multiplex imaging data sets to aid clinical decision-making processes in cancer diagnostics. 

• Single-cell transcriptomics and epigenomics – Generating single-cell libraries that measure the transcriptome and the epigenome of patient samples, specifically single-cell RNA-seq and ATAC-seq. The successful candidate will use both existing experimental protocols and computational pipelines to generate and analyze datasets for the characterization of prostate and pancreatic tumors.

Select references:

• https://www.nature.com/articles/s41467-021-27615-8
• https://www.eu-focus.europeanurology.com/article/S2405-4569(23)00077-9/fulltext
• https://www.biorxiv.org/content/10.1101/2023.08.18.553854v1

• M.D., M.D./Ph.D., or Ph.D.
• Minimum of 3 years as a graduate student
• Specialty: Molecular Biology, cell biology, genome sciences, epigenomics, or related field
• Excellent communication, analytical and organizational skills
• Ability to work independently and as part of a team while being collaborative in resolving problems
• Passion for science and inquiry
• Ability to synthesize one’s own results and others to formulate hypotheses
• Ability to prioritize multiple tasks at one time
• Must possess energy and drive to coordinate multiple projects simultaneously
• Ability to use tact and diplomacy to maintain effective working relationships

• Ability to synthesize scientific projects and communicate science to diverse audiences
• Experience with cell culture
• Experience with microscopy
• Experience with NGS
• Experience with data analysis
• Experience with patient sample processing

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

 

We offer a variety of benefits on top of joining a thriving organization:

• Medical, dental and vision coverage at no or low cost to employees
  • Covered 100% for full-time employees and 88% for dependents
• Several retirement plans to choose from with contributions from OHSU
• 80 hours of vacation time per year
• 96 hours of sick leave a year (prorated for part-time employees)
• Commuter subsidies
• Tuition reimbursement
• Access to group life insurance, disability insurance and other supplemental benefits
• Annual Raises
• Growth/Development Opportunities
• Employee discounts to local and major businesses

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Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.