The School of Dentistry shares the mission of the Oregon Health & Science University to provide educational programs, basic and clinical research, and high quality care and community programs. We strive to foster an environment of mutual respect where the free exchange of ideas can flourish. The dental school prepares graduates in general dentistry and the dental specialties to deliver compassionate and ethical oro-facial health care. Read more about the School of Dentistry: OHSU School of Dentistry

The successful candidate will work independently to investigate the molecular mechanisms supporting polymicrobial pathogenesis in  dysbiotic diseases including oral cancer. He/she will be responsible for most of the planning, implementation, and data interpretation associated with his/her research. Thus, the candidate will be expected to work independently with attention to detail and strong record-keeping. The goal is to understand how polymicrobial communities influence the development of diseases via metabolic cross-feeding and signaling transduction. To achieve this goal, we are particularly interested to improve animal models used to simulate the development of oral cancer and other inflammatory conditions driven by polymicrobial communities. Typical laboratory techniques often require expertise with animal models, molecular biology skills including northern blot, western blot, protein expression/purification, coimmunoprecipitation, gene expression analysis, and targeted mutagenesis,  microbial  analysis and microscopic skills.

 

Demonstrable experience with animal models and microbiome studies as well as these techniques is preferred. As a postdoctoral scholar, the candidate may also be involved with the training and supervision of students and junior staff as well as play an integral role in the management and supply ordering for the laboratory. Assistance with the development and preparation of grants/manuscripts will also be expected.

• Doctorate degree in (biomedical sciences, genetics, biochemistry/molecular biology, microbiology, immunology, or another relevant field)
• Demonstrable experience with some or all of the following: cancer animal models, microbiome studies, bacterial genetics, protein chemistry, proteomics, coimmunoprecipitation, RNA purification/analysis, gene expression/transcriptomics, bacterial community analysis, cell culture, and FACS analysis of host cells
• Grant and/or manuscript preparation experience
• Planning, implementation, and data interpretation experience
• Excellent oral and written communication skills
• Organizational and time management skills that maintain timeliness of work and accurate prioritization
• Ability to train and supervise students and junior staff
• Attention to detail and strong record keeping experience/skills

 

• Doctoral degree and/or postdoctoral research related to microbiome/cancer/diet
• Experience/knowledge of cancer animal models, the microbiome, especially the oral and gut flora
• Experience with microbiome-host interactions 

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.