Error: The job that you were looking for either does not exist or is no longer open.
Click column header to sort
CEDAR funds its own research projects, expediting the process of discovery. Our research is milestone-driven to ensure that each project is fulfilling its stated goals. CEDAR offers a unique opportunity for outstanding, driven, and creative postdoctoral fellows to perform cutting edge and high-risk research, ranging from understanding basic cancer biology to developing novel technologies to aid detection. Our focus on early detection requires novel approaches to reliably identify small/rare signals in diverse data types, with an emphasis on minimally invasive sampling techniques.
We are currently hiring for a highly motivated fellow with expertise in Computational Biology to work in the following areas. Candidate would primarily work with Dr. Ece Eksi, Assistant Professor in the Division of Oncological Sciences with affiliations in the Biomedical Engineering and Cell, Development and Cancer Biology departments.
- Image computing – Performing analysis of existing imaging data sets of prostate tumor samples using established pipelines and developing novel machine learning approaches. The successful candidate will have the opportunity to analyze single-cell, multiplex imaging data sets and develop image computing pipelines to aid clinical decision-making processes in cancer diagnostics.
- Machine Learning/Statistics– Developing machine learning methods and spatial statistical models to study the organization of the cell types in the tumor microenvironment using cutting-edge spatial imaging datasets. Developed algorithms will be used to build predictive temporal models for patient stratification. Techniques such as spatial auto-correlation, dimensionality reduction and clustering will be utilized.
- Single-cell transcriptomics and epigenomics - Modeling and analyzing next-generation sequencing datasets that measure the transcriptome and the epigenome, specifically single-cell RNA-seq and ATAC-seq. The successful candidate will use both existing tools and develop their own computational methods to analyze such datasets for the characterization of prostate and pancreatic tumors.
Select references:
- https://www.nature.com/articles/s41467-021-27615-8
- https://www.eu-focus.europeanurology.com/article/S2405-4569(23)00077-9/fulltext
- https://www.biorxiv.org/content/10.1101/2023.08.18.553854v1
CEDAR funds its own research projects, expediting the process of discovery. Our research is milestone-driven to ensure that each project is fulfilling its stated goals. CEDAR offers a unique opportunity for outstanding, driven, and creative postdoctoral fellows to perform cutting edge and high-risk research, ranging from understanding basic cancer biology to developing novel technologies to aid detection. Our focus on early detection requires novel approaches to reliably identify small/rare signals in diverse data types, with an emphasis on minimally invasive sampling techniques.
We are currently hiring for a highly motivated fellow with expertise in Cancer Biology to work in the following areas. Candidate would primarily work with Dr. Ece Eksi, Assistant Professor in the Division of Oncological Sciences with affiliations in the Biomedical Engineering and Cell, Development and Cancer Biology departments.
- Spatial imaging of the prostate tumor microenvironment – Performing multiplex imaging on patient samples acquired from prostate and pancreatic cancer patients to analyze intercellular interactions across cells in the microenvironment. The successful candidate will have the opportunity to learn existing experimental protocols and computational pipelines to generate and analyze single-cell, multiplex imaging data sets to aid clinical decision-making processes in cancer diagnostics.
- Single-cell transcriptomics and epigenomics– Generating single-cell libraries that measure the transcriptome and the epigenome of patient samples, specifically single-cell RNA-seq and ATAC-seq. The successful candidate will use both existing experimental protocols and computational pipelines to generate and analyze datasets for the characterization of prostate and pancreatic tumors.
Select references:
- https://www.nature.com/articles/s41467-021-27615-8
- https://www.eu-focus.europeanurology.com/article/S2405-4569(23)00077-9/fulltext
- https://www.biorxiv.org/content/10.1101/2023.08.18.553854v1
A Postdoctoral Scholar position with a bioinformatics/computational, experimental, or dual focus is available immediately in the laboratory of Dr. Brian J. O’Roak, Department of Molecular and Medical Genetics at Oregon Health & Science University (OHSU) for highly motivated individuals. Highlights of Dr. O’Roak’s past research successes include: pioneering trio-based exome sequencing in simplex autism and developing new technologies for rapid and economical targeted resequencing.
We are building on this experience by forming a strong and diverse research group focused on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular diagnosis, functional dissection of pathways, and targeted therapeutics for neurodevelopmental and related disorders. This work has the potential to dramatically improve the lives of individuals affected with these currently untreatable disorders through early intervention and biologically based personal therapies.
Areas of interest include: genomics, single-cell genomics, modeling of neurodevelopmental disorders in stem cell (iPSC) and animal systems, massively parallel functional assays, and bioinformatics.
In particular, there is an immediate need for a fellow with next-generation sequence analysis experience to lead a project exploring the role of germline mutations and somatic mosaicism in autism and other neurodevelopmental disorders (e.g. neural tube detects), for which long-term funding currently exists. This would build on our work recently published in the AJHG (see Krupp et al. 2017).
Salary for this position aligns with the NIH Scale.
The successful candidate will work as Project Leader on a variety of projects under the direction of Andrew W McHill, PhD, Assistant Professor and Director of the Sleep, Chronobiology, and Health Laboratory within the OHSU School of Nursing. The Postdoctoral fellow will work on research that is aimed at understanding the effects of disturbed sleep and circadian rhythms on physiology and pathophysiology in humans. In particular, we are investigating the adverse health effects of short and disrupted sleeping patterns, food choice, shift work, and the mechanisms underlying the adverse health of performing activities during the night. These studies will lead to interventions designed to improve the health, safety and well-being of shift-workers and vulnerable populations.
Primary duties will include data collection and management, developing scientific ideas, writing grant applications and manuscripts, and supervision of research staff. The successful candidate will be proficient in project management and independently monitoring study operations, budget management and managing human subjects IRB protocols and modifications. Shift work and weekend work (including night-time data collection) is expected. Additional duties can include overseeing and managing research equipment, materials, and logistics (with the assistance of research staff).
Experience with making measurements in human physiology, data analysis, and overseeing research studies is required. Experience with circadian, sleep, or nutritional studies, measurement of cardiovascular and metabolic variables, accelerometry, and experience with longitudinal data are desirable.
To apply please use OHSU iRecruitment to upload a letter of application, Curriculum Vitae/Resume, contact information for three academic/professional references, and a published paper.
We are looking for a post-doctoral researcher with a background in computer, information, or data science, with an interest in stream processing. This will focus on development of algorithms to process data in near-real time as it streams to servers from research participants. This position is anticipated to last 1.5-3 years to allow adequate time for the researcher to integrate with the team, understand the current platform infrastructure and data streams, and contribute to the research. Position may be hybrid with possibility of becoming remote, with workspace available at OHSU’s main campus in Portland, OR. Some travel may be required for conference presentations.
The work being done as part of this postdoctoral fellowship will support projects focused on aging in place, spanning from Mexican Americans to cancer survivors, and early detection and monitoring of Alzheimer’s disease.
There will be expectations and opportunities for publishing results and presenting at conferences.
The Layton Aging & Alzheimer’s Center in the Department of Neurology at Oregon Health & Science University seeks a post-doctoral researcher.
This position will support an ongoing NIA-funded R01 (Kevin Duff: PI) that is examining short-term practice effects on cognitive tests and measures of daily functioning in older adults with intact and impaired cognition. This position will also assist with analyses of previously completed projects and ongoing center projects, dissemination of those findings, data collection for ongoing projects, and supervision of research staff. We are looking for a post-doctoral researcher with an interest in cognition in later life, neuropsychological research, and Alzheimer’s disease.
This position is anticipated to last 1.5 - 3 years to allow adequate time for the researcher to integrate with the team, understand the available data, and generate and submit multiple manuscripts on these projects.
Current research projects a post-doctoral scholar could be involved with include the following:
- Practice Effects of Daily Functioning Across the Alzheimer’s Disease Spectrum (PFX): This is an ongoing NIA-funded R01 to examine short-term practice effects on cognitive and daily functioning tests in older adults with intact or impaired cognition.
- Amyloid Positivity and Practice Effects (APPE): This is a recently completed NIA-funded R01 that examined short-term practice effects on cognitive tests and how they relate to various biomarkers of Alzheimer’s disease.
- Validation of Video Administration of a Modified UDSv3 Cognitive Battery (VCog): OHSU is 1 of 11 sites for this ongoing NIA-funded R01 to examine if video administration of the UDS cognitive battery is as accurate as in-person administration.
- Healthy Aging & Alzheimer’s Research Program (HARP): This is OHSU’s longitudinal cohort of intact and impaired older adults who receive the UDS cognitive battery (and other measures) as part of their participation in the National Alzheimer’s Coordinating Center.
Please include a cover letter with your application.
- Primary Research (including planning, granting, execution, analysis, publication)
- a. Maintain laboratory compliance documentation for human, animal, biological and radiological work.
b. Be familiar with lab safety infrastructure and ensure compliance with all safety regulations.
c. Interact with biosafety, chemical safety, and safety officers on behalf of the Principal Investigator.
- a. Generate data and research analysis for investigator's use in preparation of technical reports and publications.
b. Assist the PI with manuscript preparation and grant applications.
c. Present, or assist in the presentation of, research projects at retreats, seminars, conferences and other OHSU or public venues.
- Providing training to users on lab practices and protocols, including sample preparation and instrumentation use.
- Maintain an accurate and detailed laboratory notebook of all experiments performed. Participate in lab meeting.
- Training of lab personnel and supervision of Research Assistants, students and other lab members.
- Perform routine lab operations, including but not limited to the purchase of laboratory supplies, monitoring supplies and maintaining all laboratory equipment.
- Other responsibilities as assigned by the supervisor in furtherance of the lab’s research and the university’s missions and goals of teaching, research, patient care, outreach and public service.
- Preforming laboratory research; Conducting experiments; Collecting, analyzing, and quantifying data; Assisting in planning and designing standard research operations, training and mentoring lab members.
- Preparation and/or review of reports, manuscripts and peer reviewed journals for publication. Submit applications for grant funding in support of the labs research mission.
- Attending and presenting research at lab meetings, seminars and conferences.
A full-time, three-year postdoctoral fellowship position is available in the Parkinson’s Center of Oregon at Oregon Health & Science University in Portland Oregon. The center conducts cutting-edge research into Parkinson’s disease including investigating the underlying biology as well as evaluating potential therapeutic options in both preclinical and human studies.
Although the incidence of Parkinson’s Disease in minoritized populations in the US seems similar, minoritized groups appear to be less often diagnosed and treated for the condition (including participation in clinical trials), which is an opportunity for further investigation and involvement by researchers.
The goals of the position are:
- Engage neurology and neuroscience researchers from minoritized groups to receive postdoctoral training in Parkinson’s disease research.
- Develop junior scientists and clinician-researchers that will interact and network with the local neuroscience community and support diverse research in the Parkinson’s disease field.
- Promote an action-oriented effort to increase diversity in the national and international academic community.
The postdoctoral position would be within one of the following labs:
Unni Lab
Martin Lab
Gray Lab
Greg Scott Lab
Balance Disorders Lab
Sleep & Health Applied Research Program (SHARP) lab
North American Prodromal Synucleinopathy (NAPS) consortium lab
Applicants should contact the lab of interest for more information on the application process.
Applicants are also encouraged to share with us any challenges or obstacles they have experienced that would contribute to the goals of this position.
- Live tissue dissection, confocal microscopy, spatial transcriptomics.
- Electrophysiology and data analysis.
- Presentation of their research at multi-PI meetings and research conferences.
- Data analysis and manuscript preparation.
- Provides research coordination and project management for multi-year research projects and assists in planning design, procedures, and performing research studies on research volunteers.
- Prepares written reports, documents, grant applications, correspondence, and peer-reviewed publications.
- Trains, mentors, and supervises research assistants, students, and junior staff.
- Performs other duties as assigned
- Provides research coordination and project management for multi-year research projects and assists in planning design, procedures, and performing research studies on research volunteers.
- Prepares written reports, documents, grant applications, correspondence, and peer-reviewed publications.
- Trains, mentors, and supervises research assistants, students, and junior staff.
- Performs other duties as assigned.
Every Knight Cancer employee is expected to embody our guiding principles:
- We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
- We SUPPORT each other—Respect leads to trust, which leads to excellence
- We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone Always Yes
Laboratory research:
- Cell culture experiments and maintenance of cells
- Assist with media changes and drug administration during experiment
- Prepare, run, and analyze flow cytometry samples
- Independently participates in research execution and performs other general laboratory techniques
- Provides stability and continuity of knowledge as people and projects change
- Meet regularly with team to identify potential synergies and reduce inefficiencies across projects
- Increased innovation and problem solving ability required
Data Analysis
- Perform qualitative and quantitative research data analysis, programming, database development and management, research data visualization, and interpretation of a wide variety of research data, especially flow cytometry data.
- Prepares reports, charts, tables, and other visual aids to interpret and communicate data and results with a variety of programs, especially R, Excel.
- Conducts data/statistical studies in support of research proposals and protocols. Maintains and develops research gathering, retrieval and reporting systems.
Laboratory Organization and Compliance:
- Responsible for managing project samples and ensure project data is properly recorded and stored
- Organizes program work space
- Ordering and maintaining supplies for lab.
Lab Support
- Support overall lab function by maintaining and fixing equipment, ordering supplies, and troubleshooting instrument problems
- Training and supervising of students and RA’s, and/or preparation of written reports and, as applicable, regulatory documentation
Additional duties as assigned by project leader or laboratory manager.
-
Participate in lab work and research
-
Develop innovative research projects and tools
-
Prepare results for publication and presentation
-
Attend and present technical status reports at group meetings
-
Planning and designing research experiments; establishing priorities and schedules; obtaining cost estimates.
-
Data collection, processing and analysis, including statistical analyses, presentation of project results, and producing written documents (abstracts, manuscripts) on the result of analyses. Includes contributing to preparation of grant proposals to NIH and private foundations.
-
Training new staff, graduate students, and student volunteers
A postdoctoral researcher position is available in the laboratory of Dr. Sarah F. Andres at the Pape Family Pediatric Research Institute, Oregon Health and Science University, Portland, OR.
We are looking for an enthusiastic, highly motivated, and dedicated Ph.D. scientist who has experience with gastrointestinal biology, extracellular vesicles, or mouse models to join our team.
The postdoc will lead projects centered around novel mechanisms that enhance or reduce intestinal damage during the neonatal inflammatory disease necrotizing enterocolitis (NEC). Ongoing projects include defining therapeutic roles of human milk extracellular vesicles in the neonatal intestine and the use of novel genetic mouse models to delineate post-transcriptional regulation in early intestinal development and NEC.
The lab uses genetic mouse models, human patient samples, including novel 3D patient-derived enteroids, cutting-edge molecular biology, -omics approaches, and imaging techniques to answer critical questions.
In addition to scientific training, the postdoc will also receive personalized mentoring to advance their own career development including networking introductions, goal setting, leadership opportunities, further training in public speaking, project management, grant, and manuscript writing, and chances to review manuscripts and attend conferences.
Our research is highly translational with the ultimate aim of taking bench findings back to educate bedside treatments and practices. Successful candidates will be dynamic, self-starters with a doctoral degree. Strong communication, organizational skills, and the ability to think critically are essential.
- Design and conduct independent research projects related to cytoskeletal reorganization during bacterial infection.
- Assist in training and supervision of new lab personnel.
- Maintain an accurate lab notebook detailing all experimental and computational work completed.
- Maintain compliance documentation for tissue culture and infection work.
- Attend Lab meeting, make contributions to grants and publications, present research at conferences.
- Other responsibilities as assigned by the supervisor in furtherance of the lab’s research and the university’s missions and goals of teaching, research, patient care, outreach and public service.
Generate and grow iPSCs and human retinal organoids, evaluate therapeutics in the generated iPSCs and retinal organoids, characterize retinal disease features and gain a mechanistic understanding for the development of retinitis pigmentosa retinal disease.
Prepare manuscripts and regularly present data at internal and external meetings.
The successful candidate will work independently to investigate the molecular mechanisms supporting polymicrobial pathogenesis in dysbiotic diseases including oral cancer. He/she will be responsible for most of the planning, implementation, and data interpretation associated with his/her research. Thus, the candidate will be expected to work independently with attention to detail and strong record-keeping. The goal is to understand how polymicrobial communities influence the development of diseases via metabolic cross-feeding and signaling transduction. To achieve this goal, we are particularly interested to improve animal models used to simulate the development of oral cancer and other inflammatory conditions driven by polymicrobial communities. Typical laboratory techniques often require expertise with animal models, molecular biology skills including northern blot, western blot, protein expression/purification, coimmunoprecipitation, gene expression analysis, and targeted mutagenesis, microbial analysis and microscopic skills.
Demonstrable experience with animal models and microbiome studies as well as these techniques is preferred. As a postdoctoral scholar, the candidate may also be involved with the training and supervision of students and junior staff as well as play an integral role in the management and supply ordering for the laboratory. Assistance with the development and preparation of grants/manuscripts will also be expected.
A Postdoctoral position in Cell, Cancer or Molecular Biology is available at the Knight Cancer Institute's Center for Experimental Therapeutics (CET). Interested candidates are expected to have recently obtained their PhD and have a strong track record of publications in Cell, Cancer or Molecular biology. Job duties include performing research to understand the role of newly identified drivers in the pathogenesis of cancer so as to identify novel therapeutic targets. The translational research projects within CET leverage multi-disciplinary approach in biology, chemistry, pharmacology, molecular modeling, in vitro and patient-derived models to probe complex biological processes and to pursue new therapeutic opportunities for various diseases. As a member of multi-disciplinary team, the postdoctoral candidate will receive training in various aspects of drug discovery & development for his/her career development.
Duties include:
- Perform hands-on experiments (in vitro and in vivo) and analyze/interpret data on assigned projects
- Critically evaluate relevant scientific advances and integrate this knowledge into research programs. Participate in project planning and execution
- Publish research in peer-reviewed journals and present work at scientific conferences. Effectively write and/or communicate research and regulatory materials. Attend and present at the project and group meetings and national conferences